Bone Marrow Transplant

Bone Marrow Transplant

The medical procedure of bone marrow

Transplantation is performed to replace diseased bone marrow with healthy bone marrow stem cell.

The new stem cells are introduced to kick start the production of new blood cells which was hindered by the diseased bone marrow. It can be performed in two different ways –

Autologous Transplant

Allogeneic Transplant

Where the patient’s own healthy stem cells are harvested before killing the diseased stem cells with chemotherapy. Once the infected stem cells are taken care of, the healthy ones are introduced back into the patient’s body.

Where the healthy stem cells are collected from a donor who is of a close genetic match with the patient. A closer match ensures a more successful transplant.


This medical procedure can give rise to more than one complication.

The most common ones are –

Graft – versus – host disease which arises when the newly introduced donor cells attack the patient’s own body.

Graft failure occurs when the transplanted stem cells fail to produce new cells defeating the whole purpose of the transplantation.

Internal bleeding in lungs, brain and other body parts.

Anemia which occurs due to the lack of red blood cells in the body.

The immunity of the patient is brought down so it doesn’t interfere with the newly introduced stem cell.

This gives rise to various infections.

Nausea, diarrhea and vomiting is often caused due to general infections. Mucositis is also common among patients which causes inflammation and soreness in their mouth, stomach and throat.

A sudden dip in the blood pressure due to the reduction of the blood cells in the body.

Fever accompanied with chills is also very common.

Damage to vital organs

Although the complication might seem to be a little overwhelming, with the right guidance and treatment from a good doctor will make this life saving procedure a whole lot smoother.

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